Recombinant Human EIF2AK1 Protein, His-tagged

• Cat.No.: EIF2AK1-1412H
• Product Overview: Recombinant Human EIF2AK1 Protein (Phe167-Phe583) with N-His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 51.1 kDa
  Accurate Molecular Mass: 51 kDa
• Protein length: Phe167-Phe583
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 [ Homo sapiens (human) ]
• Official Symbol: EIF2AK1
• Synonyms: EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1; heme regulated initiation factor 2 alpha kinase; HRI; KIAA1369; heme-regulated inhibitor; heme-regulated repressor; heme-controlled repressor; heme sensitive initiation factor 2a kinase; heme-regulated initiation factor 2-alpha kinase; hemin-sensitive initiation factor 2-alpha kinase; heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; HCR
• Gene ID: 27102
• mRNA Refseq: NM_001134335
• Protein Refseq: NP_001127807
• MIM: 613635
• UniProt ID: Q9BQI3