Recombinant Human EIF3I Protein, GST-tagged
Cat.No. : | EIF3I-3187H |
Product Overview : | Human EIF3S2 full-length ORF ( NP_003748.1, 1 a.a. - 325 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | EIF3I (Eukaryotic Translation Initiation Factor 3 Subunit I) is a Protein Coding gene. Among its related pathways are Viral mRNA Translation and Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S. GO annotations related to this gene include translation initiation factor activity. An important paralog of this gene is STRAP. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 62.9 kDa |
AA Sequence : | MKPILLQGHERSITQIKYNREGDLL FTVAKDPIVNVWYSVNGERLGTYMG HTGAVWCVDADWDTKHVLTGSADNS CRLWDCETGKQLALLKTNSAVRTCG FDFGGNIIMFSTDKQMGYQCFVSFF DLRDPSQIDNNEPYMKIPCNDSKIT SAVWGPLGECIIAGHESGELNQYSA KSGEVLVNVKEHSRQINDIQLSRDM TMFVTASKDNTAKLFDSTTLEHQKT FRTERPVNSAALSPNYDHVVLGGGQ EAMDVTTTSTRIGKFEARFFHLAFE EEFGRVKGHFGPINSVAFHPDGKSY SSGGEDGYVRIHYFDPQYFEFEFEA |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | EIF3I eukaryotic translation initiation factor 3, subunit I [ Homo sapiens ] |
Official Symbol : | EIF3I |
Synonyms : | EIF3I; eukaryotic translation initiation factor 3, subunit I; EIF3S2, eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3 subunit I; eIF3 beta; eIF3 p36; eIF3i; TRIP 1; eIF-3-beta; predicted protein of HQ2242; TGFbeta receptor-interacting protein 1; TGF-beta receptor-interacting protein 1; eukaryotic translation initiation factor 3 subunit 2; eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); TRIP1; EIF3S2; TRIP-1; PRO2242; eIF3-p36; eIF3-beta; |
Gene ID : | 8668 |
mRNA Refseq : | NM_003757 |
Protein Refseq : | NP_003748 |
MIM : | 603911 |
UniProt ID : | Q13347 |
Products Types
◆ Recombinant Protein | ||
EIF3I-2633R | Recombinant Rat EIF3I Protein (1-325 aa), His-tagged | +Inquiry |
Eif3i-2781M | Recombinant Mouse Eif3i Protein, Myc/DDK-tagged | +Inquiry |
EIF3I-1719R | Recombinant Rat EIF3I Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF3I-2062R | Recombinant Rat EIF3I Protein | +Inquiry |
EIF3I-223H | Recombinant Human EIF3I protein, T7-tagged | +Inquiry |
◆ Lysates | ||
EIF3I-6658HCL | Recombinant Human EIF3I 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (6)
Ask a questionThe protein is part of the EIF3 complex, which is involved in mRNA recognition and ligation by interacting with other EIF3 subunits, facilitating the post-transcriptional protein translation process.
EIF3I protein may be associated with cell cycle regulation. Some studies have shown that the expression level of EIF3I protein may vary at different stages of the cell cycle, but the specific regulatory mechanism needs further study.
Yes, the EIF3I protein can interact with other EIF3 subunits to form the EIF3 complex. The interaction between these subunits is to synergistically regulate the progress of protein synthesis.
Yes, there are differences in the expression levels of EIF3I protein in different tissues. For example, in some tumor tissues, the expression level of the EIF3I protein is significantly elevated.
EIF3I protein is associated with the occurrence and progression of a variety of diseases. For example, in some tumor cells, elevated levels of EIF3I protein are associated with enhanced proliferation, invasion, and metastasis of tumor cells. In addition, the EIF3I protein has been linked to some neurological diseases, such as Parkinson's disease.
There are currently no specific drugs designed to regulate the expression or function of the EIF3I protein. However, drug discovery targeting the EIF3 complex may affect the function of the EIF3I protein.
Customer Reviews (3)
Write a reviewStability of EIF3I is very good, and it can maintain a stable performance even after multiple uses, which gives me more confidence in the experimental results.
The band positions of EIF3I in Western blot were accurate and showed good specificity.
Their service attitude is very good, always patiently answer our questions.
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