Description : |
This gene encodes a purine-converting ectoenzyme which belongs to the ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDase) family. The encoded protein hydrolyzes extracellular nucleoside triphosphates (UTP, GTP, and CTP) to nucleoside monophosphates as part of a purinergic signaling pathway. It contains two transmembrane domains at the N- and C-termini and a large, hydrophobic catalytic domain located in between. This gene affects oxidative stress as well as DNA damage and is a mediator of senescence. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
69 kDa |
AA Sequence : |
MARISFSYLCPASWYFTVPTVSPFL RQRVAFLGLFFISCLLLLMLIIDFR HWSASLPRDRQYERYLARVGELEAT DTEDPNLNYGLVVDCGSSGSRIFVY FWPRHNGNPHDLLDIKQMRDRNSQP VVKKIKPGISAMADTPEHASDYLRP LLSFAAAHVPVKKHKETPLYILCTA GMRLLPERKQLAILADLVKDLPLEF DFLFSQSQAEVISGKQEGVYAWIGI NFVLGRFDHEDESDAEATQELAAGR RRTVGILDMGGASLQIAYEVPTSTS VLPAKQEEAAKILLAEFNLGCDVQH TEHVYRVYVTTFLGFGGNFARQRYE DLVLNETLNKNRLLGQKTGLSPDNP FLDPCLPVGLTDVVERNSQVLHVRG RGDWVSCGAMLSPLLARSNTSQASL NGIYQSPIDFNNSEFYGFSEFFYCT EDVLRIGGRYHGPTFAKAAQDYCGM AWSVLTQRFKNGLFSSHADEHRLKY QCFKSAWMYQVLHEGFHFPYDYPNL RTAQLVYDREVQWTLGAILYKTRFL PLRDLRQEGVRQAHGSWFRLSFVYN HYLFFACILVVLLAIFLYLLRLRRI HHRQTRASAPLDLLWLEEVVPMMGV QVGPTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |