Description : |
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
110.33 kDa |
AA Sequence : |
MARARPPPPPSPPPGLLPLLPPLLL LPLLLLPAGCRALEETLMDTKWVTS ELAWTSHPESGWEEVSGYDEAMNPI RTYQVCNVRESSQNNWLRTGFIWRR DVQRVYVELKFTVRDCNSIPNIPGS CKETFNLFYYEADSDVASASSPFWM ENPYVKVDTIAPDESFSRLDAGRVN TKVRSFGPLSKAGFYLAFQDQGACM SLISVRAFYKKCASTTAGFALFPET LTGAEPTSLVIAPGTCIPNAVEVSV PLKLYCNGDGEWMVPVGACTCATGH EPAAKESQCRPCPPGSYKAKQGEGP CLPCPPNSRTTSPAASICTCHNNFY RADSDSADSACTTVPSPPRGVISNV NETSLILEWSEPRDLGGRDDLLYNV ICKKCHGAGGASACSRCDDNVEFVP RQLGLTERRVHISHLLAHTRYTFEV QAVNGVSGKSPLPPRYAAVNITTNQ AAPSEVPTLRLHSSSGSSLTLSWAP PERPNGVILDYEMKYFEKSEGIAST VTSQMNSVQLDGLRPDARYVVQVRA RTVAGYGQYSRPAEFETTSERGSGA QQLQEQLPLIVGSATAGLVFVVAVV VIAIVCLRKQRHGSDSEYTEKLQQY IAPGMKVYIDPFTYEDPNEAVREFA KEIDVSCVKIEEVIGAGEFGEVCRG RLKQPGRREVFVAIKTLKVGYTERQ RRDFLSEASIMGQFDHPNIIRLEGV VTKSRPVMILTEFMENCALDSFLRL NDGQFTVIQLVGMLRGIAAGMKYLS EMNYVHRDLAARNILVNSNLVCKVS DFGLSRFLEDDPSDPTYTSSLGGKI PIRWTAPEAIAYRKFTSASDVWSYG IVMWEVMSYGERPYWDMSNQDVINA VEQDYRLPPPMDCPTALHQLMLDCW VRDRNLRPKFSQIVNTLDKLIRNAA SLKVIASAQSGMSQPLLDRTVPDYT TFTTVGDWLDAIKMGRYKESFVSAG FASFDLVAQMTAEDLLRIGVTLAGH QKKILSSIQDMRLQMNQTLPVQVTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |