Recombinant Human EPHX2 Protein, His-tagged
Cat.No. : | EPHX2-584H |
Product Overview : | Active human recombinant N-terminal His-tagged EPHX2 protein was purified from Sf21 cells. |
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Description : | Mammalian soluble epoxide hydrolase (sEH) is a member of the α/β-hydrolase fold family of enzymes that catalyzes the hydrolysis of exogenous and endogenous epoxides to vicinal diols. sEH is a homodimer consisting of two domains. The C-terminal domain is responsible for the epoxide hydrolase activity while the N-terminal domain has a catalytic center with phosphatase activity. Endogenous substrates for sEH include epoxyeicosatrienoic acids (EETs) which are known for their vasodialatory effects as well as for their anti-inflammatory actions. Inhibition of sEH in animal models was shown to reduce hypertension and vascular inflammation, as well as related syndromes, validating sEH as a highly promising target for drug discovery. |
Source : | Insect Cell |
Species : | Human |
Tag : | His |
Molecular Mass : | 64 kDa |
Purity : | ≥95% estimated by SDS-PAGE |
Unit Definition : | One unit hydrolyzes 1 nmol/min of PHOME at 37 centigrade. Detected by fluorescence of product; Ex. 330 nm, Em. 465 nm and measured against a standard curve of 6-methoxy-2-napthaldehyde. |
Notes : | For research use only |
Stability : | ≥ 6 months |
Storage : | Store at -80 centigrade. |
Warning : | This product is not for human or veterinary use. |
Gene Name : | EPHX2 epoxide hydrolase 2 [ Homo sapiens (human) ] |
Official Symbol : | EPHX2 epoxide hydrolase 2 [ Homo sapiens (human) ] |
Synonyms : | EPHX2; epoxide hydrolase 2; Cytosolic Epoxide Hydrolase (CEH); EPHX2; Epoxide Hydrolase 2; sEH; CEH; SHE; bifunctional epoxide hydrolase 2; epoxide hydratase; epoxide hydrolase 2, cytoplasmic; epoxide hydrolase 2, cytosolic; epoxide hydrolase, soluble; EC 3.1.3.76; EC 3.3.2.10 |
Gene ID : | 2053 |
mRNA Refseq : | NM_001256482 |
Protein Refseq : | NP_001243411 |
MIM : | 132811 |
UniProt ID : | P34913 |
Products Types
◆ Recombinant Protein | ||
EPHX2-3409H | Recombinant Human EPHX2 Protein, GST-tagged | +Inquiry |
EPHX2-056H | Recombinant Human EPHX2 Protein, His-tagged | +Inquiry |
EPHX2-1781R | Recombinant Rat EPHX2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ephx2-960M | Recombinant Mouse Ephx2 Protein, MYC/DDK-tagged | +Inquiry |
EPHX2-34H | Recombinant Human EPHX2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
EPHX2-6585HCL | Recombinant Human EPHX2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Write a reviewThe product brochure is very detailed and has comprehensive basic information about the EPHX2 protein.
The staff actively communicated with me and solved many technical problems.
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