Recombinant Human ERN1 Protein, MYC/DDK-tagged

• Cat.No.: ERN1-2226H
• Product Overview: Recombinant human ERN1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 109.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ERN1 endoplasmic reticulum to nucleus signaling 1 [ Homo sapiens ]
• Official Symbol: ERN1
• Synonyms: hIRE1p; IRE1; IRE1a; IRE1P
• Gene ID: 2081
• mRNA Refseq: NM_001433
• Protein Refseq: NP_001424
• MIM: 604033
• UniProt ID: O75460