Recombinant Human ETHE1, His-tagged

• Cat.No.: ETHE1-28332TH
• Product Overview: Recombinant full length mature protein of Human ETHE1 (amino acids 13-254) with a N terminal His tag. 267 amino acids with a predicted MWt of 29.1kDa including the tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 242 amino acids
• Description: This gene encodes a sulfur dioxygenase that localizes within the mitochondrial matrix. The enzyme functions in sulfide catabolism. Mutations in this gene result in ethylmalonic encephalopathy.
• Conjugation: HIS
• Molecular Weight: 29.100kDa inclusive of tags
• Tissue specificity: Ubiquitously expressed.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMLSQRG GSGAPILLRQ MFEPVSCTFT YLLGDRESRE AVLIDPVLET APRDAQLIKE LGLRLLYAVN THCHADHITG SGLLRSLLPG CQSVISRLSG AQADLHIEDG DSIRFGRFAL ETRASPGHTP GCVTFVLNDH SMAFTGDALL IRGCGRTDFQ QGCAKTLYHS VHEKIFTLPG DCLIYPAHDY HGFTVSTVEE ERTLNPRLTL SCEEFVKIMG NLNLPKPQQI DFAVPANMRC GVQTPTA
• Sequence Similarities: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

Gene Information

• Gene Name: ETHE1 ethylmalonic encephalopathy 1 [ Homo sapiens ]
• Official Symbol: ETHE1
• Synonyms: ETHE1; ethylmalonic encephalopathy 1; protein ETHE1, mitochondrial; HSCO; YF13H12
• Gene ID: 23474
• mRNA Refseq: NM_014297
• Protein Refseq: NP_055112
• MIM: 608451
• Uniprot ID: O95571
• Chromosome Location: 19q13.32
• Function: hydrolase activity; metal ion binding