Recombinant Human EXO5 Protein, GST-tagged EXO5-2531H

Recombinant Human EXO5 Protein, GST-tagged

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Recombinant Human EXO5 Protein, GST-tagged

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Cat.No. : EXO5-2531H
Product Overview : Human DEM1 full-length ORF ( NP_073611.1, 1 a.a. - 373 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 68.2 kDa
AA Sequence : MAETREEETV SAEASGFSDL SDSEFLEFLD LEDAQESKAL VNMPGPSSES LGKDDKPISL QNWKRGLDIL SPMERFHLKY LYVTDLATQN WCELQTAYGK ELPGFLAPEK AAVLDTGASI HLARELELHD LVTVPVTTKE DAWAIKFLNI LLLIPTLQSE GHIREFPVFG EGEGVLLVGV IDELHYTAKG ELELAELKTR RRPMLPLEAQ KKKDCFQVSL YKYIFDAMVQ GKVTPASLIH HTKLCLEKPL GPSVLRHAQQ GGFSVKSLGD LMELVFLSLT LSDLPVIDIL KIEYIHQETA TVLGTEIVAF KEKEVRAKVQ HYMAYWMGHR EPQGVDVEEA WKCRTCTYAD ICEWRKGSGV LSSTLAPQVK KAK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : EXO5 exonuclease 5 [ Homo sapiens (human) ]
Official Symbol : EXO5
Synonyms : DEM1; defects in morphology 1 homolog (S. cerevisiae); C1orf176, chromosome 1 open reading frame 176; probable exonuclease V; FLJ21144; defects in morphology protein 1 homolog; Exo V; C1orf176; FLJ11445; FLJ13183; EXO5; exonuclease 5
Gene ID : 64789
mRNA Refseq : NM_022774
Protein Refseq : NP_073611
UniProt ID : Q9H790

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