Recombinant Human EXOSC1 Protein, GST-tagged

• Cat.No.: EXOSC1-3566H
• Product Overview: Human EXOSC1 full-length ORF ( AAH22067, 1 a.a. - 195 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 47.19 kDa
• AA Sequence: MAPPVRYCIPGERLCNLEEGSPGSG TYTRHGYIFSSLAGCLMKSSENGAL PVVSVVRETESQLLPDVGAIVTCKV SSINSRFAKVHILYVGSMPLKNSFR GTIRKEDVRATEKDKVEIYKSFRPG DIVLAKVISLGDAQSNYLLTTAENE LGVVVAHSESGIQMVPISWCEMQCP KTHTKEFRKVARVQPEFLQT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EXOSC1 exosome component 1 [ Homo sapiens ]
• Official Symbol: EXOSC1
• Synonyms: EXOSC1; exosome component 1; exosome complex component CSL4; CGI 108; CSL4; CSL4 exosomal core protein homolog (yeast); Csl4p; hCsl4p; p13; SKI4; Ski4p; exosomal core protein CSL4; 3-5 exoribonuclease CSL4 homolog; CSL4 exosomal core protein homolog; homolog of yeast exosomal core protein CSL4; CGI-108; RP11-452K12.9
• Gene ID: 51013
• mRNA Refseq: NM_016046
• Protein Refseq: NP_057130
• MIM: 606493
• UniProt ID: Q9Y3B2