Recombinant Human EXOSC8 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EXOSC8-5452H
• Product Overview: EXOSC8 MS Standard C13 and N15-labeled recombinant protein (NP_852480) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 30 kDa
• AA Sequence: MAAGFKTVEPLEYYRRFLKENCRPD GRELGEFRTTTVNIGSISTADGSAL VKLGNTTVICGVKAEFAAPSTDAPD KGYVVPNVDLPPLCSSRFRSGPPGE EAQVASQFIADVIENSQIIQKEDLC ISPGKLVWVLYCDLICLDYDGNILD ACTFALLAALKNVQLPEVTINEETA LAEVNLKKKSYLNIRTHPVATSFAV FDDTLLIVDPTGEEEHLATGTLTIV MDEEGKLCCLHKPGGSGLTGAKLQD CMSRAVTRHKEVKKLMDEVIKSMKP KTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EXOSC8 exosome component 8 [ Homo sapiens (human) ]
• Official Symbol: EXOSC8
• Synonyms: EXOSC8; exosome component 8; exosome complex component RRP43; bA421P11.3; CBP interacting protein 3; CIP3; EAP2; OIP2; Opa interacting protein 2; p9; RRP43; Rrp43p; OIP-2; CBP-interacting protein 3; opa-interacting protein 2; exosome complex exonuclease RRP43; ribosomal RNA-processing protein 43; RP11-421P11.3
• Gene ID: 11340
• mRNA Refseq: NM_181503
• Protein Refseq: NP_852480
• MIM: 606019
• UniProt ID: Q96B26