Recombinant Human F2RL1 Protein, His-tagged

• Cat.No.: F2RL1-2177H
• Product Overview: Recombinant Human F2RL1 Protein (Val309-Tyr397) with a N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 13.8 kDa
  Accurate Molecular Mass: 14 kDa
• Protein length: Val309-Tyr397
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: F2RL1 F2R like trypsin receptor 1 [ Homo sapiens (human) ]
• Official Symbol: F2RL1
• Synonyms: F2rl1; F2R like trypsin receptor 1; Par2; Par-2; proteinase-activated receptor 2
  Proteinase-activated receptor-2, G protein-coupled receptor 11
  coagulation factor II (thrombin) receptor-like 1
  coagulation factor II receptor-like 1
  thrombin receptor-like 1
• Gene ID: 2150
• mRNA Refseq: NM_005242
• Protein Refseq: NP_005233
• MIM: 600933
• UniProt ID: P55085