Recombinant Human FBXW9 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FBXW9-461H
• Product Overview: FBXW9 MS Standard C13 and N15-labeled recombinant protein (NP_115677) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50.6 kDa
• AA Sequence: MELPLGRCDDSRTWDDDSDPESETD PDAQAKAYVARVLSPPKSGLAFSRP SQLSTPAASPSASEPRAASRVSAVS EPGLLSLPPELLLEICSYLDARLVL HVLSRVCHALRDLVSDHVTWRLRAL RRVRAPYPVVEEKNFDWPAACIALE QHLSRWAEDGRWVEYFCLAEGHVAS VDSVLLLQGGSLCLSGSRDRNVNLW DLRQLGTESNQVLIKTLGTKRNSTH EGWVWSLAAQDHRVCSGSWDSTVKL WDMAADGQQFGEIKASSAVLCLSYL PDILVTGTYDKKVTIYDPRAGPALL KHQQLHSRPVLTLLADDRHIISGSE DHTLVVVDRRANSVLQRLQLDSYLL CMSYQEPQLWAGDNQGLLHVFANRN GCFQLIRSFDVGHSFPITGIQYSVG ALYTTSTDKTIRVHVPTDPPRTICT RRHDNGLNRVCAEGNLVVAGSGDLS LEVWRLQATRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FBXW9 F-box and WD repeat domain containing 9 [ Homo sapiens (human) ]
• Official Symbol: FBXW9
• Synonyms: FBXW9; F-box and WD repeat domain containing 9; F box and WD 40 domain protein 9; F-box/WD repeat-containing protein 9; Fbw9; MGC10870; F-box and WD-40 domain protein 9; F-box and WD-40 domain-containing protein 9; F-box and WD-40 repeat containing protein 9; specificity factor for SCF ubiquitin ligase
• Gene ID: 84261
• mRNA Refseq: NM_032301
• Protein Refseq: NP_115677
• MIM: 609074
• UniProt ID: Q5XUX1