Recombinant Human FCGR3A Protein, DYKDDDDK-tagged
Cat.No. : | FCGR3A-151H |
Product Overview : | Recombinant Human Fc fragment of IgG receptor IIIa(FCGR3A), transcript variant 1(NM_000569), with a DYKDDDDK tag, was expressed in human cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | Human cells |
Species : | Human |
Tag : | DYKDDDDK |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.241, without any preservatives. |
Molecular Mass : | 22.61kD |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name : | FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) [ Homo sapiens ] |
Official Symbol : | FCGR3A |
Synonyms : | FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16) , FCG3, FCGR3; low affinity immunoglobulin gamma Fc region receptor III-A; CD16; CD16a; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; igG Fc receptor III-2; Fc gamma receptor III-A; Fc-gamma receptor IIIb (CD16); neutrophil-specific antigen NA; Fc-gamma receptor III-2 (CD 16); immunoglobulin G Fc receptor III; Fc fragment of IgG, low affinity III, receptor for (CD16); FCG3; CD16A; FCGR3; IGFR3; FCR-10; FCRIII; FCGRIII; FCRIIIA; |
Gene ID : | 2214 |
mRNA Refseq : | NM_000569 |
Protein Refseq : | NP_000560 |
MIM : | 146740 |
UniProt ID : | P08637 |
Products Types
◆ Recombinant Protein | ||
FCGR3A-100H | Active Recombinant Human FCGR3A protein(Met1-Gln208,176F), His-Avi-tagged | +Inquiry |
FCGR3A-02H | Active Recombinant Human FCGR3A Protein (18-208aa), C-His-tagged | +Inquiry |
FCGR3A-625H | Active Recombinant Human FCGR3A, His-tagged, 176 Phe | +Inquiry |
FCGR3A-3995H | Recombinant Human FCGR3A Protein | +Inquiry |
FCGR3A-547H | Recombinant Human FCGR3A Protein (V176) | +Inquiry |
◆ Lysates | ||
FCGR3A-1969RCL | Recombinant Rat FCGR3A cell lysate | +Inquiry |
FCGR3A-001HCL | Recombinant Human FCGR3A cell lysate | +Inquiry |
FCGR3A-1999HCL | Recombinant Human FCGR3A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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