Recombinant Human FCRL3, His-tagged

• Cat.No.: FCRL3-12830H
• Product Overview: Recombinant Human FCRL3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-302a.a.
• Description: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FCRL3 Fc receptor-like 3 [ Homo sapiens ]
• Official Symbol: FCRL3
• Synonyms: FCRL3; Fc receptor-like 3; Fc receptor-like protein 3; CD307c; FCRH3; IFGP3; IRTA3; SPAP2; SPAP2a; SPAP2b; SPAP2c; SPAP2d; SPAP2e; hIFGP3; fcR-like protein 3; Fc receptor homolog 3; IFGP family protein 3; SH2 domain-containing phosphatase anchor protein 2; immune receptor translocation-associated protein 3; immunoglobulin superfamily receptor translocation associated protein 3
• Gene ID: 115352
• mRNA Refseq: NM_052939
• Protein Refseq: NP_443171
• MIM: 606510
• UniProt ID: Q96P31
• Chromosome Location: 1q21-q22
• Pathway: T Cell Receptor Signaling Pathway, organism-specific biosystem
• Function: receptor activity