Recombinant Human FEV Protein, GST-tagged

• Cat.No.: FEV-4080H
• Product Overview: Human FEV full-length ORF ( NP_059991.1, 1 a.a. - 238 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 51.4 kDa
• AA Sequence: MRQSGASQPLLINMYLPDPVGDGLF KDGKNPSWGPLSPAVQKGSGQIQLW QFLLELLADRANAGCIAWEGGHGEF KLTDPDEVARRWGERKSKPNMNYDK LSRALRYYYDKNIMSKVHGKRYAYR FDFQGLAQACQPPPAHAHAAAAAAA AAAAAQDGALYKLPAGLAPLPFPGL SKLNLMAASAGVAPAGFSYWPGPGP AATAAAATAALYPSPSLQPPPGPFG AVAAASHLGGHYH
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FEV FEV (fifth Ewing variant) [ Homo sapiens ]
• Official Symbol: FEV
• Synonyms: FEV; FEV (fifth Ewing variant); Pet-1; protein FEV; FEV (ETS oncogene family); PC12 ETS domain-containing transcription factor 1; fifth Ewing variant protein
• Gene ID: 54738
• mRNA Refseq: NM_017521
• Protein Refseq: NP_059991
• MIM: 607150
• UniProt ID: Q99581