Recombinant Human FGD1 Protein, MYC/DDK-tagged

• Cat.No.: FGD1-1969H
• Product Overview: Recombinant human FGD1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 106.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FGD1 FYVE, RhoGEF and PH domain containing 1 [ Homo sapiens ]
• Official Symbol: FGD1
• Synonyms: AAS; FGDY; MRXS16; ZFYVE3
• Gene ID: 2245
• mRNA Refseq: NM_004463
• Protein Refseq: NP_004454
• MIM: 300546
• UniProt ID: P98174