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Recombinant Human FGFR2 protein(IIIb), His-Avi-tagged
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| Cat.No. : | FGFR2-055H |
| Product Overview : | Recombinant Human FGFR2 alpha (IIIb) Protein is expressed from mammalian with a His tag and Avi Tag at the C-terminal. It contains Arg22-Glu378. |
| Description : | Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | His-Avi |
| Form : | Supplied as 0. 22um filtered solution in PBS (pH 7. 4). |
| Molecular Mass : | The protein has a predicted MW of 42. 5 kDa. Due to glycosylation, the protein migrates to 70-110KDa based on Bis-Tris PAGE result. |
| Protein length : | It contains Arg22-Glu378. |
| Endotoxin : | Less than 0. 05 EU per ug by the LAL method. |
| Purity : | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
| Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
| Tris-Bis PAGE : |
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| HPLC data : |
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| Gene Name : | FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ] |
| Official Symbol : | FGFR2 |
| Synonyms : | FGF R2a; FGFR2 alpha;KGFR;CD332;Keratinocyte growth factor receptor |
| Gene ID : | 2263 |
| mRNA Refseq : | NM_000141 |
| Protein Refseq : | NP_000132 |
| MIM : | 176943 |
| UniProt ID : | P21802 |
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