Recombinant Human FGFR2 protein(IIIb), His-Avi-tagged

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Recombinant Human FGFR2 protein(IIIb), His-Avi-tagged

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Cat.No. : FGFR2-055H
Product Overview : Recombinant Human FGFR2 alpha (IIIb) Protein is expressed from mammalian with a His tag and Avi Tag at the C-terminal. It contains Arg22-Glu378.
Description : Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha  isoform, or only IgII and IgIII, referred to as the beta  isoform.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0. 22um filtered solution in PBS (pH 7. 4).
Molecular Mass : The protein has a predicted MW of 42. 5 kDa. Due to glycosylation, the protein migrates to 70-110KDa based on Bis-Tris PAGE result.
Protein length : It contains Arg22-Glu378.
Endotoxin : Less than 0. 05 EU per ug by the LAL method.
Purity : > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :

HPLC data :

Gene Name : FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ]
Official Symbol : FGFR2
Synonyms : FGF R2a; FGFR2 alpha;KGFR;CD332;Keratinocyte growth factor receptor
Gene ID : 2263
mRNA Refseq : NM_000141
Protein Refseq : NP_000132
MIM : 176943
UniProt ID : P21802

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