Recombinant Human FKBP10 Protein, Myc/DDK-tagged
Cat.No. : | FKBP10-58H |
Product Overview : | Recombinant protein of human FK506 binding protein 10, 65 kDa (FKBP10) with a C-Myc/DDK tag was expressed in HEK293T. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined. |
Source : | HEK293T |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 64.1 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | FKBP10 FKBP prolyl isomerase 10 [ Homo sapiens (human) ] |
Official Symbol : | FKBP10 |
Synonyms : | FKBP10; FKBP prolyl isomerase 10; OI6; OI11; BRKS1; FKBP65; PPIASE; hFKBP65; peptidyl-prolyl cis-trans isomerase FKBP10; 65 kDa FK506-binding protein; 65 kDa FKBP; FK506 binding protein 10, 65 kDa; FK506-binding protein 10; FKBP-10; FKBP-65; PPIase FKBP10; immunophilin FKBP65; rotamase; EC 5.2.1.8 |
Gene ID : | 60681 |
mRNA Refseq : | NM_021939 |
Protein Refseq : | NP_068758 |
MIM : | 607063 |
UniProt ID : | Q96AY3 |
Products Types
◆ Recombinant Protein | ||
FKBP10-915H | Recombinant Human FKBP10 Protein, His (Fc)-Avi-tagged | +Inquiry |
FKBP10-4182H | Recombinant Human FKBP10 Protein, GST-tagged | +Inquiry |
Fkbp10-3019M | Recombinant Mouse Fkbp10 Protein, Myc/DDK-tagged | +Inquiry |
FKBP10-1538R | Recombinant Rhesus Macaque FKBP10 Protein, His (Fc)-Avi-tagged | +Inquiry |
Fkbp10-1290M | Recombinant Mouse Fkbp10 protein, His-tagged | +Inquiry |
◆ Lysates | ||
FKBP10-6213HCL | Recombinant Human FKBP10 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe expression of FKBP10 is regulated by a variety of factors. For example, some growth factors, such as EGF and TGF-β, can induce their expression, while some drugs and other small molecule compounds can also affect their expression levels.
The protein can participate in the regulation of immune response by interacting with a variety of immune-related proteins. For example, it can exert immunosuppressive effects by inhibiting T cell activation and inflammatory responses.
FKBP10 can interact with a variety of proteins and molecules. For example, it can interact with HSP90 to form complexes to exert its functions, and it can also interact with a variety of immune-related molecules such as IL-2, IL-6, and IFN-γ to modulate immune responses.
It can promote angiogenesis. It promotes the formation of new blood vessels by promoting endothelial cell proliferation and migration, as well as inhibiting apoptosis of vascular endothelial cells.
FKBP10 can affect the apoptosis process through a variety of pathways. For example, it can inhibit NF-κB signaling, which inhibits cell survival signaling, and it can also promote the release of pro-apoptotic molecules such as cytochrome c from mitochondria.
It can interact with a variety of proteins, binding to target proteins through its FKBP12-like domain, thereby promoting protein folding and stability.
Customer Reviews (3)
Write a reviewThe quality is very good and in line with relevant industry standards.
FKBP10 has strong anti-pollution ability and is not easy to be polluted, which ensures the quality of the product.
When it is used in experiments, the results are accurate, reliable, and very reliable.
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