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Recombinant Human FKBP10 Protein, Myc/DDK-tagged

Cat.No. : FKBP10-58H
Product Overview : Recombinant protein of human FK506 binding protein 10, 65 kDa (FKBP10) with a C-Myc/DDK tag was expressed in HEK293T.
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Description : The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.
Source : HEK293T
Species : Human
Tag : Myc/DDK
Molecular Mass : 64.1 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Gene Name : FKBP10 FKBP prolyl isomerase 10 [ Homo sapiens (human) ]
Official Symbol : FKBP10
Synonyms : FKBP10; FKBP prolyl isomerase 10; OI6; OI11; BRKS1; FKBP65; PPIASE; hFKBP65; peptidyl-prolyl cis-trans isomerase FKBP10; 65 kDa FK506-binding protein; 65 kDa FKBP; FK506 binding protein 10, 65 kDa; FK506-binding protein 10; FKBP-10; FKBP-65; PPIase FKBP10; immunophilin FKBP65; rotamase; EC 5.2.1.8
Gene ID : 60681
mRNA Refseq : NM_021939
Protein Refseq : NP_068758
MIM : 607063
UniProt ID : Q96AY3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How is FKBP10 expression regulated? 06/20/2022

The expression of FKBP10 is regulated by a variety of factors. For example, some growth factors, such as EGF and TGF-β, can induce their expression, while some drugs and other small molecule compounds can also affect their expression levels.

What is the mechanism by which FKBP10 regulates the immune response? 03/21/2022

The protein can participate in the regulation of immune response by interacting with a variety of immune-related proteins. For example, it can exert immunosuppressive effects by inhibiting T cell activation and inflammatory responses.

Which is the interaction between FKBP10 and other proteins or molecules? 08/22/2021

FKBP10 can interact with a variety of proteins and molecules. For example, it can interact with HSP90 to form complexes to exert its functions, and it can also interact with a variety of immune-related molecules such as IL-2, IL-6, and IFN-γ to modulate immune responses.

What is the role of FKBP10 in angiogenesis? 06/14/2021

It can promote angiogenesis. It promotes the formation of new blood vessels by promoting endothelial cell proliferation and migration, as well as inhibiting apoptosis of vascular endothelial cells.

How does FKBP10 affect the apoptotic process? 05/24/2020

FKBP10 can affect the apoptosis process through a variety of pathways. For example, it can inhibit NF-κB signaling, which inhibits cell survival signaling, and it can also promote the release of pro-apoptotic molecules such as cytochrome c from mitochondria.

Is FKBP10 involved in the regulation of protein folding and stability? 12/01/2019

It can interact with a variety of proteins, binding to target proteins through its FKBP12-like domain, thereby promoting protein folding and stability.

Customer Reviews (3)

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Reviews
06/28/2023

    The quality is very good and in line with relevant industry standards.

    12/21/2020

      FKBP10 has strong anti-pollution ability and is not easy to be polluted, which ensures the quality of the product.

      03/02/2020

        When it is used in experiments, the results are accurate, reliable, and very reliable.

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