Recombinant Human FMO2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FMO2-3131H
• Product Overview: FMO2 MS Standard C13 and N15-labeled recombinant protein (NP_001451) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53.6 kDa
• AA Sequence: MAKKVAVIGAGVSGLISLKCCVDEG LEPTCFERTEDIGGVWRFKENVEDG RASIYQSVVTNTSKEMSCFSDFPMP EDFPNFLHNSKLLEYFRIFAKKFDL LKYIQFQTTVLSVRKCPDFSSSGQW KVVTQSNGKEQSAVFDAVMVCSGHH ILPHIPLKSFPGMERFKGQYFHSRQ YKHPDGFEGKRILVIGMGNSGSDIA VELSKNAAQVFISTRHGTWVMSRIS EDGYPWDSVFHTRFRSMLRNVLPRT AVKWMIEQQMNRWFNHENYGLEPQN KYIMKEPVLNDDVPSRLLCGAIKVK STVKELTETSAIFEDGTVEENIDVI IFATGYSFSFPFLEDSLVKVENNMV SLYKYIFPAHLDKSTLACIGLIQPL GSIFPTAELQARWVTRVFKGLCSLP SERTMMMDIIKRNEKRIDLFGESQS QTLQTNYVDYLDELALEIGAKPDFC SLLFKDPKLAVRLYFGPCNSYTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FMO2 flavin containing dimethylaniline monoxygenase 2 [ Homo sapiens (human) ]
• Official Symbol: FMO2
• Synonyms: FMO2; flavin containing monooxygenase 2 (non-functional); flavin containing monooxygenase 2; dimethylaniline monooxygenase [N-oxide-forming] 2; FMO 2; FMO 1B1; FMO, pulmonary; dimethylaniline oxidase 2; pulmonary flavin-containing monooxygenase 2; FMO1B1; FLJ40826
• Gene ID: 2327
• mRNA Refseq: NM_001460
• Protein Refseq: NP_001451
• MIM: 603955
• UniProt ID: Q99518