Recombinant Human FNIP2 Protein, His-tagged
Cat.No. : | FNIP2-171H |
Product Overview : | Recombinant Human folliculin interacting protein 2(FNIP2), transcript variant 1(NM_020840), with a His tag, was expressed in human cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the folliculin-interacting protein family. The encoded protein binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK) and be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This protein may also play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. A homologous binding partner of this protein, folliculin-interacting protein 1, has similar binding activities and may suggest functional redundancy within this protein family. Both folliculin-interacting proteins have also been shown to bind the molecular chaperone heat shock protein-90 (Hsp90) and they may function as a co-chaperones in the stabilization of tumor suppressor folliculin which is a target of Hsp90 chaperone activity. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.53, without any preservatives. |
Molecular Mass : | 121.9 kDa |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name : | FNIP2 folliculin interacting protein 2 [ Homo sapiens ] |
Official Symbol : | FNIP2 |
Synonyms : | FNIP2; folliculin interacting protein 2; folliculin-interacting protein 2; FNIPL; KIAA1450; FNIP1-like protein; O6-methylguanine-induced apoptosis 1 protein; MAPO1; |
Gene ID : | 57600 |
mRNA Refseq : | NM_020840 |
Protein Refseq : | NP_065891 |
MIM : | 612768 |
UniProt ID : | Q9P278 |
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◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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