Recombinant Human Follistatin
Cat.No. : | FST-1617H |
Product Overview : | Recombinant Human follistatinexpressed inSf21 cells using a baculovirus expression system. And A DNA sequence encoding amino acid residues Gly 30 to Asp 329 of the human Follistatin precursor was fused to the signal peptide of human CD33, inserted into a suitable expression vector. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FST-1617H |
Description : | Follistatin (FST) is a glycosylated single-chain protein. It specifically inhibits the secretion of FSH from the pituitary. Follistatin/activin-binding protein binds to heparan sulfate side chains of proteoglycans on the granulosa cell surface to regulate the various actions of activin. Follistatin regulates a variety of biological functions, including cell proliferation, differentiation, and apoptosis. Follistatin plays a critical role in the production of multiple-organ metastasis, predominantly by inhibiting the angiogenesis. |
Source : | Sf21 Insect Cells. |
Molecular Weight : | The predicted molecular weight of Recombinant Human FS is 31 kDa. However, the actual molecular weight as observed by migration on SDS Page is 40 kDa. |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Biological Activity : | The biological activity of Human FS was determined by its ability to neutralize Activin-induced bioactivity on K562 cells (erythroid differentiation). The expected ED50 for this effect is typically 0.1 - 0.4 μg/mL in the presence of 7.5 ng/mL of rhActivin A. |
Gene Name : | FST follistatin [ Homo sapiens ] |
Synonyms : | EFNA5; ephrin-A5; AF1; EFL5; RAGS; EPLG7; GLC1M; LERK7 ; eph-related receptor tyrosine kinase ligand 7; LERK-7; AL-1; LERK-7; ephrin-A5 |
Gene ID : | 10468 |
mRNA Refseq : | NM_006350 |
Protein Refseq : | NP_006341 |
MIM : | 136470 |
UniProt ID : | P19883 |
Chromosome Location : | 5q11.2 |
Pathway : | TGF-beta signaling pathway |
Function : | heparan sulfate proteoglycan binding; protein binding; signal transducer activity |
Products Types
◆ Recombinant Protein | ||
FST-6937H | Active Recombinant Human FST protein, His-tagged | +Inquiry |
FST-2667H | Recombinant Human FST Protein, MYC/DDK-tagged | +Inquiry |
FST-4524H | Recombinant Human FST Protein, GST-tagged | +Inquiry |
Fst-2759R | Recombinant Rat Fst Protein, His-tagged | +Inquiry |
FST-2054R | Recombinant Rat FST Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FST-1833HCL | Recombinant Human FST cell lysate | +Inquiry |
FST-1771MCL | Recombinant Mouse FST cell lysate | +Inquiry |
FST-001MCL | Recombinant Mouse FST cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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