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Recombinant Human FOLR2 Protein, His-tagged

Cat.No. : FOLR2-254H
Product Overview : Recombinant human FOLR2 protein with His tag was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Source : HEK293
Species : Human
Tag : His
Form : Lyophilized
Molecular Mass : 26 kDa
Protein Length : 255
AA Sequence : MVWKWMPLLLLLVCVATMCSAQDRT DLLNVCMDAKHHKTKPGPEDKLHDQ CSPWKKNACCTASTSQELHKDTSRL YNFNWDHCGKMEPACKRHFIQDTCL YECSPNLGPWIQQVNQSWRKERFLD VPLCKEDCQRWWEDCHTSHTCKSNW HRGWDWTSGVNKCPAGALCRTFESY FPTPAALCEGLWSHSYKVSNYSRGS GRCIQMWFDSAQGNPNEEVARFYAA AMHVNAGEMLHGTGGLLLSLALMLQ LWLLG
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : FOLR2 folate receptor 2 (fetal) [ Homo sapiens (human) ]
Official Symbol : FOLR2
Synonyms : FOLR2; folate receptor 2 (fetal); folate receptor beta; FBP; folate receptor, beta; folate receptor, fetal/placental; placental folate-binding protein; folate-binding protein, fetal/placental; FR-P3; FR-BETA; BETA-HFR; FBP/PL-1;
Gene ID : 2350
mRNA Refseq : NM_000803
Protein Refseq : NP_000794
MIM : 136425
UniProt ID : P14207

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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