Recombinant Human FYCO1 Protein, GST-tagged

• Cat.No.: FYCO1-4584H
• Product Overview: Human FYCO1 full-length ORF ( AAH07218, 1 a.a. - 255 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 53.79 kDa
• AA Sequence: MNTKVTSDWYYARSPFLQPKLSSDI VGQLYELTEVQFDLASRGFDLDAAW PTFARRTLTTGSSAYLWKPPSRSSS MSSLVSSYLQTQEMVSNFDLNSPLN NEALEGFDEMRLELDQLEVREKQLQ ERMQQLDRENQELRAAVSQQGEQLQ TERERGRTAAEDNVRLTCLVAELQK QWEVTQATQNTVKELQTCLQALELG AAEKEEDYHTALRRLESMLQPLAQE LEATRDSLDKKNQHLASFPGWLAMA LHVGD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FYCO1 FYVE and coiled-coil domain containing 1 [ Homo sapiens ]
• Official Symbol: FYCO1
• Synonyms: FYCO1; FYVE and coiled-coil domain containing 1; FYVE and coiled-coil domain-containing protein 1; FLJ13335; ZFYVE7; RUN and FYVE domain containing 3; zinc finger FYVE domain-containing protein 7; CATC2; RUFY3; MGC126517; MGC126519; DKFZp779K1152
• Gene ID: 79443
• mRNA Refseq: NM_024513
• Protein Refseq: NP_078789
• MIM: 607182
• UniProt ID: Q9BQS8