Recombinant Human G6PC3 Protein, GST-tagged

• Cat.No.: G6PC3-4614H
• Product Overview: Human G6PC3 full-length ORF ( NP_612396.1, 1 a.a. - 346 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 65.1 kDa
• AA Sequence: MESTLGAGIVIAEALQNQLAWLENV WLWITFLGDPKILFLFYFPAAYYAS RRVGIAVLWISLITEWLNLIFKWFL FGDRPFWWVHESGYYSQAPAQVHQF PSSCETGPGSPSGHCMITGAALWPI MTALSSQVATRARSRWVRVMPSLAY CTFLLAVGLSRIFILAHFPHQVLAG LITGAVLGWLMTPRVPMERELSFYG LTALALMLGTSLIYWTLFTLGLDLS WSISLAFKWCERPEWIHVDSRPFAS LSRDSGAALGLGIALHSPCYAQVRR AQLGNGQKIACLVLAMGLLGPLDWL GHPPQISLFYIFNFLKYTLWPCLVL ALVPWAVHMFSAQEAPPIHSS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: G6PC3 glucose-6-phosphatase catalytic subunit 3 [ Homo sapiens (human) ]
• Official Symbol: G6PC3
• Synonyms: G6PC3; glucose-6-phosphatase catalytic subunit 3; SCN4; UGRP; glucose-6-phosphatase 3; G-6-Pase 3; G6Pase 3; G6Pase-beta; glucose 6 phosphatase, catalytic, 3; ubiquitous glucose-6-phosphatase catalytic subunit-related protein; ubiquitously expressed G6Pase catalytic subunit-related protein; EC 3.1.3.9
• Gene ID: 92579
• mRNA Refseq: NM_001319945
• Protein Refseq: NP_001306874
• MIM: 611045
• UniProt ID: Q9BUM1