Recombinant Human GABRB2 Protein, GST-tagged

• Cat.No.: GABRB2-4646H
• Product Overview: Human GABRB2 full-length ORF ( NP_000804.1, 1 a.a. - 474 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 81 kDa
• AA Sequence: MWRVRKRGYFGIWSFPLIIAAVCAQ SVNDPSNMSLVKETVDRLLKGYDIR LRPDFGGPPVAVGMNIDIASIDMVS EVNMDYTLTMYFQQAWRDKRLSYNV IPLNLTLDNRVADQLWVPDTYFLND KKSFVHGVTVKNRMIRLHPDGTVLY GLRITTTAACMMDLRRYPLDEQNCT LEIESYGYTTDDIEFYWRGDDNAVT GVTKIELPQFSIVDYKLITKKVVFS TGSYPRLSLSFKLKRNIGYFILQTY MPSILITILSWVSFWINYDASAARV ALGITTVLTMTTINTHLRETLPKIP YVKAIDMYLMGCFVFVFMALLEYAL VNYIFFGRGPQRQKKAAEKAASANN EKMRLDVNKMDPHENILLSTLEIKN EMATSEAVMGLGDPRSTMLAYDASS IQYRKAGLPRHSFGRNALERHVAQK KSRLRRRASQLKITIPDLTDVNAID RWSRIFFPVVFSFFNIVYWLYYVN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 [ Homo sapiens ]
• Official Symbol: GABRB2
• Synonyms: GABRB2; gamma-aminobutyric acid (GABA) A receptor, beta 2; gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor; beta 2; GABA(A) receptor, beta 2; GABA(A) receptor subunit beta-2; gamma-aminobutyric acid A receptor beta 2; MGC119386; MGC119388; MGC119389
• Gene ID: 2561
• mRNA Refseq: NM_000813
• Protein Refseq: NP_000804
• MIM: 600232
• UniProt ID: P47870