Recombinant Human GCH1 Protein, His-tagged
Cat.No. : | GCH1-801H |
Product Overview : | Recombinant Human GCH1 fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Molecular Mass : | 27.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | GCH1 GTP cyclohydrolase 1 [ Homo sapiens ] |
Official Symbol : | GCH1 |
Synonyms : | GCH1; GTP cyclohydrolase 1; dystonia 14 , DYT5, DYT14, GCH; dopa responsive dystonia; DYT5a; GTPCH1; GTP-CH-I; dystonia 14; GTP cyclohydrolase I; guanosine 5-triphosphate cyclohydrolase I; GCH; DYT5; DYT14; HPABH4B; GTP-CH-1; |
Gene ID : | 2643 |
mRNA Refseq : | NM_001024070 |
Protein Refseq : | NP_001019241 |
MIM : | 600225 |
UniProt ID : | P30793 |
Products Types
◆ Recombinant Protein | ||
GCH1-2197H | Recombinant Human GCH1 Protein, His-tagged | +Inquiry |
GCH1-3504M | Recombinant Mouse GCH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
GCH1-2145R | Recombinant Rat GCH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
GCH1-4794H | Recombinant Human GCH1 Protein, GST-tagged | +Inquiry |
GCH1-3024H | Recombinant Human GCH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GCH1-5988HCL | Recombinant Human GCH1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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