Recombinant Human GDAP1L1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human GDAP1L1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : GDAP1L1-2218H
Product Overview : GDAP1L1 MS Standard C13 and N15-labeled recombinant protein (NP_076939) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 42 kDa
AA Sequence : MATPNNLTPT NCSWWPISAL ESDAAKPAEA PDAPEAASPA HWPRESLVLY HWTQSFSSQK VRLVIAEKGL VCEERDVSLP QSEHKEPWFM RLNLGEEVPV IIHRDNIISD YDQIIDYVER TFTGEHVVAL MPEVGSLQHA RVLQYRELLD ALPMDAYTHG CILHPELTTD SMIPKYATAE IRRHLANATT DLMKLDHEEE PQLSEPYLSK QKKLMAKILE HDDVSYLKKI LGELAMVLDQ IEAELEKRKL ENEGQKCELW LCGCAFTLAD VLLGATLHRL KFLGLSKKYW EDGSRPNLQS FFERVQRRFA FRKVLGDIHT TLLSAVIPNA FRLVKRKPPS FFGASFLMGS LGGMGYFAYW YLKKKYITRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 [ Homo sapiens (human) ]
Official Symbol : GDAP1L1
Synonyms : ganglioside induced differentiation associated protein 1-like 1; 4213; Ensembl:ENSG00000124194; DKFZp761K228; ganglioside-induced differentiation-associated protein 1-like 1;GDAP1-L1; dJ881L22.1; dJ995J12.1.1
Gene ID : 78997
mRNA Refseq : NM_024034
Protein Refseq : NP_076939
UniProt ID : B7Z621

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