Recombinant Human GFM2 Protein, GST-tagged

• Cat.No.: GFM2-4854H
• Product Overview: Human GFM2 full-length ORF ( NP_115756.2, 1 a.a. - 779 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 113 kDa
• AA Sequence: MLTNLRIFAMSHQTIPSVYINNICC YKIRASLKRLKPHVPLGRNCSSLPG LIGNDIKSLHSIINPPIAKIRNIGI MAHIDAGKTTTTERILYYSGYTRSL GDVDDGDTVTDFMAQERERGITIQS AAVTFDWKGYRVNLIDTPGHVDFTL EVERCLRVLDGAVAVFDASAGVEAQ TLTVWRQADKHNIPRICFLNKMDKT GASFKYAVESIREKLKAKPLLLQLP IGEAKTFKGVVDVVMKEKLLWNCNS NDGKDFERKPLLEMNDPELLKETTE ARNALIEQVADLDDEFADLVLEEFS ENFDLLPAEKLQTAIHRVTLAQTAV PVLCGSALKNKGIQPLLDAVTMYLP SPEERNYEFLQWYKDDLCALAFKVL HDKQRGPLVFMRIYSGTIKPQLAIH NINGNCTERISRLLLPFADQHVEIP SLTAGNIALTVGLKHTATGDTIVSS KSSALAAARRAEREGEKKHRQNNEA ERLLLAGVEIPEPVFFCTIEPPSLS KQPDLEHALKCLQREDPSLKVRLDP DSGQTVLCGMGELHIEIIHDRIKRE YGLETYLGPLQVAYRETILNSVRAT DTLDRTLGDKRHLVTVEVEARPIET SSVMPVIEFEYAESINEGLLKVSQE AIENGIHSACLQGPLLGSPIQDVAI TLHSLTIHPGTSTTMISACVSRCVQ KALKKADKQVLEPLMNLEVTVARDY LSPVLADLAQRRGNIQEIQTRQDNK VVIGFVPLAEIMGYSTVLRTLTSGS ATFALELSTYQAMNPQDQNTLLNRR SGLT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GFM2 G elongation factor, mitochondrial 2 [ Homo sapiens ]
• Official Symbol: GFM2
• Synonyms: GFM2; G elongation factor, mitochondrial 2; ribosome-releasing factor 2, mitochondrial; EFG2; FLJ21661; MSTP027; mitochondrial elongation factor G2; elongation factor G 2, mitochondrial; mitochondrial ribosome recycling factor 2; RRF2; MRRF2; hEFG2; MST027; RRF2mt; EF-G2mt; mEF-G 2
• Gene ID: 84340
• mRNA Refseq: NM_032380
• Protein Refseq: NP_115756
• MIM: 606544
• UniProt ID: Q969S9