Recombinant Human GGCT Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GGCT-5520H
• Product Overview: GGCT MS Standard C13 and N15-labeled recombinant protein (NP_076956) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 21 kDa
• AA Sequence: MANSGCKDVTGPDEESFLYFAYGSN LLTERIHLRNPSAAFFCVARLQDFK LDFGNSQGKTSQTWHGGIATIFQSP GDEVWGVVWKMNKSNLNSLDEQEGV KSGMYVVIEVKVATQEGKEITCRSY LMTNYESAPPSPQYKKIICMGAKEN GLPLEYQEKLKAIEPNDYTGKVSEE IEDIIKKGETQTLTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GGCT gamma-glutamylcyclotransferase [ Homo sapiens (human) ]
• Official Symbol: GGCT
• Synonyms: GGCT; gamma-glutamylcyclotransferase; C7orf24, chromosome 7 open reading frame 24, GCTG; CRF21; Ggc; MGC3077; cytochrome c-releasing factor 21; gamma -glutamyl cyclotransferase; GGC; GCTG; C7orf24; FLJ11717
• Gene ID: 79017
• mRNA Refseq: NM_024051
• Protein Refseq: NP_076956
• MIM: 137170
• UniProt ID: O75223