Recombinant Human GJB2 Protein, GST-tagged

• Cat.No.: GJB2-4928H
• Product Overview: Human GJB2 full-length ORF ( AAH17048, 1 a.a. - 226 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 50.6 kDa
• AA Sequence: MDWGTLQTILGGVNKHSTSIGKIWL TVLFIFRIMILVVAAKEVWGDEQAD FVCNTLQPGCKNVCYDHYFPISHIR LWALQLIFVSTPALLVAMHVAYRRH EKKRKFIKGEIKSEFKDIEEIKTQK VRIEGSLWWTYTSSIFFRVIFEAAF MYVFYVMYDGFSMQRLVKCNAWPCP NTVDCFVSRPTEKTVFTVFMIAVSG ICILLNVTELCYLLIRYCSGKSKKP V
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GJB2 gap junction protein, beta 2, 26kDa [ Homo sapiens ]
• Official Symbol: GJB2
• Synonyms: GJB2; gap junction protein, beta 2, 26kDa; DFNA3, DFNB1, gap junction protein, beta 2, 26kD (connexin 26), gap junction protein, beta 2, 26kDa (connexin 26); gap junction beta-2 protein; connexin 26; CX26; NSRD1; HID; KID; PPK; DFNA3; DFNB1; DFNA3A; DFNB1A
• Gene ID: 2706
• mRNA Refseq: NM_004004
• Protein Refseq: NP_003995
• MIM: 121011
• UniProt ID: P29033