Recombinant Human Glutathione transferase zeta 1, His-tagged

• Cat.No.: GSTZ1-1947H
• Product Overview: Recombinant GSTZ1 protein fused to his-tag was expressed inE.coliand purified by using conventional chromatography techniques, 26.2 kDa (236aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-261 a.a.
• Description: GSTZ1, also known as maleylacetoacetate isomerase, is an enzyme that belongs to glutathione S-transferase (GSTs) super-family. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. It also plays a significant role in the catabolism of phenylalanine and tyrosine.
• Purity: > 95% by SDS – PAGE.
• Physical Appearance: Liquid.
• Formulation: In Phosphate Buffered Saline pH7.4 containing 10% glycerol.
• Concentration: 1.0 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP TLKIDGITIH QSLAIIEYLE ETRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRA.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Drug metabolism - cytochrome P450; Glutathione metabolism; Metabolic pathways; Metabolism of xenobiotics by cytochrome P450; Tyrosine metabolism; Metabolism of amino acids and derivatives

Gene Information

• Gene Name: GSTZ1 glutathione transferase zeta 1 [ Homo sapiens ]
• Synonyms: GSTZ1; glutathione transferase zeta 1; MAI; MAAI; GSTZ1-1; MGC2029; maleylacetone isomerase; maleylacetoacetate isomerase; glutathione S-aryltransferase; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione s-transferase Zeta 1; S-(hydroxyalkyl)glutathione lyase; EC 5.2.1.2,EC 2.5.1.18
• Gene ID: 2954
• mRNA Refseq: NM_001513
• Protein Refseq: NP_001504
• MIM: 603758
• UniProt ID: O43708
• Chromosome Location: 14q24.3
• Function: glutathione peroxidase activity; glutathione transferase activity; isomerase activity; maleylacetoacetate isomerase activity; protein binding; transferase activity