Recombinant Human GNA13 protein, GST-tagged

• Cat.No.: GNA13-187H
• Product Overview: Recombinant Human GNA13 fused with GST tag at N-terminal was expressed in E. coli.

Specification

• Description: G-alpha 13 (GNA13) is a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. It activates Rho and regulates cytoplasmic as well as nuclear signaling events such as activation of the Jun N-terminal kinase signaling module, Na+/H+ exchangers, focal adhesion assemblies, and transcriptional activation of specific primary response genes. Like GNA12, GNA13 proteins are found up-regulated in several human cancers, and the GNA12/GNA13 signaling plays an important role in cancer cell invasion and metastasis.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: 67 kDa
• Purity: >70%
• Applications: Enzyme Assay, Western Blot
• Stability: 1 year at -70 centigrade date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.05μg/μl

Gene Information

• Gene Name: GNA13 guanine nucleotide binding protein (G protein), alpha 13 [ Homo sapiens ]
• Official Symbol: GNA13
• Synonyms: GNA13; guanine nucleotide binding protein (G protein), alpha 13; guanine nucleotide-binding protein subunit alpha-13; G13; MGC46138; g alpha-13; G-protein subunit alpha-13
• Gene ID: 10672
• mRNA Refseq: NM_006572
• Protein Refseq: NP_006563
• MIM: 604406
• UniProt ID: Q14344