Recombinant Human GNAI3 Protein, His-tagged

• Cat.No.: GNAI3-2207H
• Product Overview: Recombinant Human GNAI3 Protein (Gly2-Tyr354) with a N-His tag was expressed in E. coli.

Specification

• Description: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 44.1 kDa
• Protein length: Gly2-Tyr354
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 [ Homo sapiens (human) ]
• Official Symbol: GNAI3
• Synonyms: GNAI3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3; guanine nucleotide-binding protein G(k) subunit alpha; 87U6; g(i) alpha-3; FLJ26559
• Gene ID: 2773
• mRNA Refseq: NM_006496
• Protein Refseq: NP_006487
• MIM: 139370
• UniProt ID: P08754