Recombinant Human GNAI3 protein, MYC/DDK-tagged

• Cat.No.: GNAI3-380H
• Product Overview: Recombinant Human GNAI3 fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 40.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 [ Homo sapiens ]
• Official Symbol: GNAI3
• Synonyms: 87U6; ARCND1; guanine nucleotide-binding protein G(k) subunit alpha; g(i) alpha-3
• Gene ID: 2773
• mRNA Refseq: NM_006496
• Protein Refseq: NP_006487
• MIM: 139370
• UniProt ID: P08754
• Chromosome Location: 1p13
• Pathway: ADP signalling through P2Y purinoceptor 12, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Adrenergic signaling in cardiomyocytes, organism-specific biosystem
• Function: G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity