Recombinant Human golgi associated, gamma adaptin ear containing, ARF binding protein 1 Protein, His tagged

• Cat.No.: GGA1-148H
• Product Overview: Recombinant human GGA1 protein (Q9UJY5) (Met 1-Phe 157) with a His tag at the C-terminus was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-157aa
• Description: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Required for targeting PKD1:PKD2 complex from the trans-Golgi network to the cilium membrane. Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endosomes to the trans-Golgi network.
• Tag: C-His
• Molecular Mass: 19.6 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: GGA1
• Synonyms: GGA1; golgi associated, gamma adaptin ear containing, ARF binding protein 1; ADP-ribosylation factor-binding protein GGA1; ADP-ribosylation factor binding protein 1; gamma-adaptin related protein 1; golgi-localized, gamma ear-containing, ARF-binding protein 1
• Gene ID: 26088
• mRNA Refseq: NM_013365
• Protein Refseq: NP_037497
• MIM: 606004
• UniProt ID: Q9UJY5