Recombinant Human GORASP1

• Cat.No.: GORASP1-26151TH
• Product Overview: Recombinant full length Human GRASP65 with proprietary tag; Predicted MWt 74.47 kDa.

Specification

• Description: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Several alternatively spliced transcript variants of this gene have been identified, but their full-length natures have not been determined.
• Protein length: 440 amino acids
• Molecular Weight: 74.470kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MGLGVSAEQPAGGAEGFHLHGVQEN SPAQQAGLEPYFDFIITIGHSRLNK ENDTLKALLKANVEKPVKLEVFNMK TMRVREVEVVPSNMWGGQGLLGASV RFCSFRRASEQVWHVLDVEPSSPAA LAGLRPYTDYVVGSDQILQESEDFF TLIESHEGKPLKLMVYNSKSDSCRE VTVTPNAAWGGEGSLGCGIGYGYLH RIPTQPPSYHKKPPGTPPPSALPLG APPPDALPPGPTPEDSPSLETGSRQ SDYMEALLQAPGSSMEDPLPGPGSP SHSAPDPDGLPHFMETPLQPPPPVQ RVMDPGFLDVSGISLLDNSNASVWP SLPSSTELTTTAVSTSGPEDICSSS SSHERGGEATWSGSEFEVSFLDSPG AQAQADHLPQLTLPDSLTSAASPED GLSAELLEAQAEEEPASTEGLDTGT EAEGLDSQAQISTTE
• Sequence Similarities: Belongs to the GORASP family.Contains 1 PDZ (DHR) domain.

Gene Information

• Gene Name: GORASP1 golgi reassembly stacking protein 1, 65kDa [ Homo sapiens ]
• Official Symbol: GORASP1
• Synonyms: GORASP1; golgi reassembly stacking protein 1, 65kDa; golgi phosphoprotein 5 , GOLPH5; Golgi reassembly-stacking protein 1; FLJ23443; GRASP65; P65
• Gene ID: 64689
• mRNA Refseq: NM_031899
• Protein Refseq: NP_114105
• MIM: 606867
• Uniprot ID: Q9BQQ3
• Chromosome Location: 3p22-p21.33
• Pathway: Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; Golgi Cisternae Pericentriolar Stack Reorganization, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem