Recombinant Human GP1BA Protein (17-531 aa), His-tagged
Cat.No. : | GP1BA-1401H |
Product Overview : | Recombinant Human GP1BA Protein (17-531 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cardiovascular. Protein Description: Partial. |
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- Gene Information
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Description : | GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 58.9 kDa |
Protein length : | 17-531 aa |
AA Sequence : | HPICEVSKVASHLEVNCDKRNLTAL PPDLPKDTTILHLSENLLYTFSLAT LMPYTRLTQLNLDRCELTKLQVDGT LPVLGTLDLSHNQLQSLPLLGQTLP ALTVLDVSFNRLTSLPLGALRGLGE LQELYLKGNELKTLPPGLLTPTPKL EKLSLANNNLTELPAGLLNGLENLD TLLLQENSLYTIPKGFFGSHLLPFA FLHGNPWLCNCEILYFRRWLQDNAE NVYVWKQGVDVKAMTSNVASVQCDN SDKFPVYKYPGKGCPTLGDEGDTDL YDYYPEEDTEGDKVRATRTVVKFPT KAHTTPWGLFYSWSTASLDSQMPSS LHPTQESTKEQTTFPPRWTPNFTLH MESITFSKTPKSTTEPTPSPTTSEP VPEPAPNMTTLEPTPSPTTPEPTSE PAPSPTTPEPTPIPTIATSPTILVS ATSLITPKSTFLTTTKPVSLLESTK KTIPELDQPPKLRGVLQGHLESSRN DPFLHPDFCCLLPLGFYVLGLFWLL FASVVLILLLSWVGH |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | GP1BA glycoprotein Ib (platelet), alpha polypeptide [ Homo sapiens ] |
Official Symbol : | GP1BA |
Synonyms : | GP1BA; GP1B; CD42b; GP-Ib alpha; BSS; VWDP; CD42B; GPIbA; BDPLT1; BDPLT3; DBPLT3; CD42b-alpha; MGC34595; |
Gene ID : | 2811 |
mRNA Refseq : | NM_000173 |
Protein Refseq : | NP_000164 |
MIM : | 606672 |
UniProt ID : | BC027955 |
Products Types
◆ Recombinant Protein | ||
GP1BA-5130H | Recombinant Human GP1BA Protein, GST-tagged | +Inquiry |
GP1BA-683H | Recombinant Human GP1BA Protein, His-tagged | +Inquiry |
GP1BA-16H | Recombinant Human GP1BA Protein, His-tagged | +Inquiry |
GP1BA-2584H | Recombinant Human GP1BA protein(381-450 aa), N-SUMO & C-His-tagged | +Inquiry |
GP1BA-531H | Recombinant Human GP1BA Protein (17-505 aa), His-tagged | +Inquiry |
◆ Lysates | ||
GP1BA-5823HCL | Recombinant Human GP1BA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGlycoprotein Ib platelet subunit alpha (GP1BA) plays a crucial role in platelet physiology and hemostasis, specifically in platelet adhesion.
Dysregulation or abnormal expression of GP1BA is associated with conditions such as Bernard-Soulier syndrome and other platelet disorders.
GP1BA contributes to platelet adhesion by interacting with von Willebrand factor (vWF), facilitating platelet plug formation at vascular injury sites.
Interactions or binding partners of GP1BA include vWF and other components of the platelet glycoprotein Ib-IX-V complex, influencing platelet function.
GP1BA participates in the regulation of blood clotting and coagulation cascades by initiating platelet activation and aggregation.
GP1BA is predominantly localized on the surface of platelets, especially within the platelet membrane.
There are potential therapeutic implications related to GP1BA in diseases involving platelet disorders, making it a target for drug development.
Customer Reviews (3)
Write a reviewIts compatibility with collaborative platforms and open-source tools facilitated sharing and reproducibility of our experiments.
The product's support in the form of educational resources positively impacted the learning curve for our researchers.
The product's track record of being featured in influential publications positively influenced our decision to use it.
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