Recombinant Human GPER1 Over-expression Lysate, C-Myc/DDK tagged

• Cat.No.: GPER1-58HCL
• Product Overview: GPER1 cell transient overexpression lysate (as WB positive control) with C-Myc/DDK tag was expressed in HEK293T.
  Components:
  1 vial of 20 μg lyophilized gene specific transient over-expression cell lysate

Specification

• Description: This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function.
• Source: HEK293T
• Species: Human
• Tag: C-Myc/DDK
• Molecular Mass: 42.1 kDa
• Stability: Lysate samples are stable for 12 months from date of receipt when stored at -20 centigrade.
• Storage: Upon receiving, store the sample at -20 centigrade. Avoid repeated freeze-thaw cycles after reconstitution.
• Shipping: At ambient temperature
• Reconstitution: Lysate samples can be reconstituted with SDS Sample Buffer.

Gene Information

• Gene Name: GPER1 G protein-coupled estrogen receptor 1 [ Homo sapiens (human) ]
• Official Symbol: GPER1
• Synonyms: GPER1; G protein-coupled estrogen receptor 1; mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br; G-protein coupled estrogen receptor 1; G protein-coupled receptor 30; IL8-related receptor DRY12; chemoattractant receptor-like 2; chemokine receptor-like 2; constitutively expressed peptide-like receptor; flow-induced endothelial G-protein coupled receptor 1; heptahelix receptor; lymphocyte-derived G-protein coupled receptor; membrane estrogen receptor
• Gene ID: 2852
• mRNA Refseq: NM_001098201
• Protein Refseq: NP_001091671
• MIM: 601805
• UniProt ID: Q99527