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Recombinant Human GRIK2 Protein, GST-tagged

Cat.No. : GRIK2-5337H
Product Overview : Human GRIK2 full-length ORF ( AAH37954, 1 a.a. - 353 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 64.57 kDa
AA Sequence : MKIIFPILSNPVFRRTVKLLLCLLW IGYSQGTTHVLRFGGIFEYVESGPM GAEELAFRFAVNTINRNRTLLPNTT LTYDTQKINLYDSFEASKKACDQLS LGVAAIFGPSHSSSANAVQSICNAL GVPHIQTRWKHQVSDNKDSFYVSLY PDFSSLSRAILDLVQFFKWKTVTVV YDDSTGLIRLQELIKAPSRYNLRLK IRQLPADTKDAKPLLKEMKRGKEFH VIFDCSHEMAAGILKQALAMGMMTE YYHYIFTTLDLFALDVEPYRYSGVN MTGFRILNTENTQVSSIIEKWSMER LQAPPKPDSGLLDGFMTMEFHSCCP GWSAMARSHLTAASASWVQAILLPQ PPE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GRIK2 glutamate receptor, ionotropic, kainate 2 [ Homo sapiens ]
Official Symbol : GRIK2
Synonyms : GRIK2; glutamate receptor, ionotropic, kainate 2; GLUR6; glutamate receptor, ionotropic kainate 2; GluK2; MRT6; gluR-6; bA487F5.1; glutamate receptor 6; glutamate receptor form A; glutamate receptor form B; glutamate receptor form C; glutamate receptor form D; glutamate receptor form E; excitatory amino acid receptor 4; EAA4; GLR6; GLUK6; MGC74427;
Gene ID : 2898
mRNA Refseq : NM_001166247
Protein Refseq : NP_001159719
MIM : 138244
UniProt ID : Q13002

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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