Recombinant Human GRK4 Protein, His-tagged

• Cat.No.: GRK4-392H
• Product Overview: Recombinant Human GRK4(Phe187~Phe449) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 33.8kDa
• Protein length: Phe187~Phe449
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: GRK4 G protein-coupled receptor kinase 4 [ Homo sapiens ]
• Official Symbol: GRK4
• Synonyms: GRK4; G protein-coupled receptor kinase 4; G protein coupled receptor kinase 2 like (Drosophila) , GPRK2L; GPRK4; ITI1; IT11; GRK4a; GPRK2L
• Gene ID: 2868
• mRNA Refseq: NM_001004056
• Protein Refseq: NP_001004056
• MIM: 137026
• UniProt ID: P32298