Recombinant Human Growth Arrest and DNA-damage-Inducible, Gamma

• Cat.No.: GADD45G-359H
• Product Overview: Recombinant humanGADD45G protein was expressed in E.coli and purified by using conventional chromatography techniques, 17.1 kDa (159 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: GADD45G is a member of GADD45 family (GADD45α, β, and γ) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH 7.5).
• Purity: > 95% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MTLEEVRGQD TVPESTARMQ GAGKALHELL LSAQRQGCLT AGVYESAKVL NVDPDNVTFC VLAAGEEDEG DIALQIHFTL IQAFCCENDI DIVRVGD VQ R LAAIVGAGEE AGAPGDLHCI LISNPNEDAW KDPALEKLSL FCEESRSVND WVPSITLPE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: GADD45G growth arrest and DNA-damage-inducible, gamma [ Homo sapiens ]
• Synonyms: growth arrest and DNA-damage-inducible, gamma; GADD45-gamma; OTTHUMP00000021623; gadd-related protein, 17 kD; GADD45G; DDIT2; GADD45gamma; CR6; GRP17; DDIT-2; Cytokine-responsive protein CR6; DNA-damage-inducible transcript 2.
• Gene ID: 10912
• mRNA Refseq: NM_006705
• Protein Refseq: NP_006696
• MIM: 604949
• UniProt ID: O95257
• Chromosome Location: 9q22.1-q22.2
• Function: protein binding