Recombinant Human GSTT2, GST-tagged

• Cat.No.: GSTT2-13583H
• Product Overview: Recombinant Human GSTT2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-244a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GSTT2 glutathione S-transferase theta 2 [ Homo sapiens ]
• Official Symbol: GSTT2
• Synonyms: GSTT2; glutathione S-transferase theta 2; glutathione S-transferase theta-2; GST class-theta-2; Glutathione S-transferase theta-2B; GSTT2B; MGC182032
• Gene ID: 2953
• mRNA Refseq: NM_000854
• Protein Refseq: NP_000845
• MIM: 600437
• UniProt ID: P0CG29
• Chromosome Location: 22q11.23
• Pathway: Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem
• Function: glutathione transferase activity; transferase activity