Recombinant Human GTF2A2 Protein, His-tagged
Cat.No. : | GTF2A2-419H |
Product Overview : | Recombinant Human GTF2A2 fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
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Description : | Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]). |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl. |
Molecular Mass : | 12.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | GTF2A2 general transcription factor IIA, 2, 12kDa [ Homo sapiens ] |
Official Symbol : | GTF2A2 |
Synonyms : | GTF2A2; general transcription factor IIA, 2, 12kDa; general transcription factor IIA, 2 (12kD subunit); transcription initiation factor IIA subunit 2; HsT18745; TFIIA; TFIIAS; TFIIA-12; TFIIA-gamma; TFIIA p12 subunit; general transcription factor IIA subunit 2; transcription initiation factor IIA gamma chain; TF2A2; |
Gene ID : | 2958 |
mRNA Refseq : | NM_004492 |
Protein Refseq : | NP_004483 |
MIM : | 600519 |
UniProt ID : | P52657 |
Products Types
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GTF2A2-3000H | Recombinant Human General Transcription Factor IIA, 2, 12kDa, T7-tagged | +Inquiry |
◆ Lysates | ||
GTF2A2-5704HCL | Recombinant Human GTF2A2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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