Recombinant Human GUCA2B Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: GUCA2B-368H
• Product Overview: GUCA2B MS Standard C13 and N15-labeled recombinant protein (NP_009033) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. [provided by RefSeq, Nov 2015]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 12.1 kDa
• AA Sequence: MGCRAASGLLPGVAVVLLLLLQSTQ SVYIQYQGFRVQLESMKKLSDLEAQ WAPSPRLQAQSLLPAVCHHPALPQD LQPVCASQEASSIFKTLRTIANDDC ELCVNVACTGCLTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GUCA2B guanylate cyclase activator 2B (uroguanylin) [ Homo sapiens (human) ]
• Official Symbol: GUCA2B
• Synonyms: GUCA2B; guanylate cyclase activator 2B (uroguanylin); guanylate cyclase activator 2B; uroguanylin; UGN; GCAP-II
• Gene ID: 2981
• mRNA Refseq: NM_007102
• Protein Refseq: NP_009033
• MIM: 601271
• UniProt ID: Q16661