Recombinant Human GUK1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GUK1-5223H
• Product Overview: GUK1 MS Standard C13 and N15-labeled recombinant protein (NP_000849) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 21.7 kDa
• AA Sequence: MSGPRPVVLSGPSGAGKSTLLKRLL QEHSGIFGFSVSHTTRNPRPGEENG KDYYFVTREVMQRDIAAGDFIEHAE FSGNLYGTSKVAVQAVQAMNRICVL DVDLQGVRNIKATDLRPIYISVQPP SLHVLEQRLRQRNTETEESLVKRLA AAQADMESSKEPGLFDVVIINDSLD QAYAELKEALSEEIKKAQRTGATRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GUK1 guanylate kinase 1 [ Homo sapiens (human) ]
• Official Symbol: GUK1
• Synonyms: GUK1; guanylate kinase 1; guanylate kinase; GMP kinase; ATP:GMP phosphotransferase; GMK; FLJ42686; FLJ43710
• Gene ID: 2987
• mRNA Refseq: NM_000858
• Protein Refseq: NP_000849
• MIM: 139270
• UniProt ID: Q16774