Recombinant Human GYS1, MYC/DDK-tagged

• Cat.No.: GYS1-11H
• Product Overview: Recombinant Human GYS1, fused with C-terminal MYC/DDK, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 83.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: GYS1 glycogen synthase 1 (muscle) [ Homo sapiens (human) ]
• Official Symbol: GYS1
• Synonyms: GYS1; GSY; GYS; glycogen synthase 1 (muscle); glycogen [starch] synthase, muscle; NP_001155059.1; EC 2.4.1.11; NP_002094.2
• Gene ID: 2997
• mRNA Refseq: NM_002103
• Protein Refseq: NP_002094
• MIM: 138570
• UniProt ID: P13807
• Chromosome Location: 19q13.3
• Pathway: Glucose metabolism; Insulin Signaling; Metabolism of carbohydrates
• Function: glucose binding; glycogen (starch) synthase activity; glycogen synthase activity, transferring glucose-1-phosphate