Recombinant Human H2AFV, His-tagged

• Cat.No.: H2AFV-13645H
• Product Overview: Recombinant Human H2AFV protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-128a.a.
• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: H2AFV H2A histone family, member V [ Homo sapiens ]
• Official Symbol: H2AFV
• Synonyms: H2AFV; H2A histone family, member V; H2AV; histone H2A.V; MGC1947; MGC10170; MGC10831; H2A.F/Z; histone H2A.F/Z; purine-rich binding element protein B; FLJ26479
• Gene ID: 94239
• mRNA Refseq: NM_012412
• Protein Refseq: NP_036544
• UniProt ID: Q71UI9
• Chromosome Location: 7p13
• Pathway: Systemic lupus erythematosus, organism-specific biosystem; Systemic lupus erythematosus, conserved biosystem
• Function: DNA binding