Recombinant Human H2BC21 Protein, His-tagged

• Cat.No.: H2BC21-2815H
• Product Overview: Recombinant Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat) H2BC21 Protein (Pro2-Lys126) fused with a N-His tag.

Specification

• Species: Human/Mouse/Rat
• Source: E.coli
• Tag: His
• Protein Length: Pro2-Lys126
• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 17.5 kDa
  Accurate Molecular Mass: 18 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: H2BC21 H2B clustered histone 21 [ Homo sapiens (human) ]
• Official Symbol: H2BC21
• Synonyms: H2BC21; H2B clustered histone 21; H2B; H2BE; H2BQ; GL105; H2B.1; H2BFQ; H2BGL105; H2B-GL105; HIST2H2BE; histone H2B type 2-E; H2B histone family, member Q; histone 2, H2be; histone H2B-GL105; histone H2B.q; histone cluster 2 H2B family member e; histone cluster 2, H2be
• Gene ID: 8349
• mRNA Refseq: https://NM_003528
• Protein Refseq: https://NP_003519
• MIM: 601831
• UniProt ID: Q16778