Recombinant Human HARS, GST-tagged
Cat.No. : | HARS-13669H |
Product Overview : | Recombinant Human HARS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-282a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | HARS histidyl-tRNA synthetase [ Homo sapiens ] |
Official Symbol : | HARS |
Synonyms : | HARS; histidyl-tRNA synthetase; histidine--tRNA ligase, cytoplasmic; histidine tRNA ligase 1; cytoplasmic; HisRS; histidine translase; HRS; USH3B; FLJ20491; |
Gene ID : | 3035 |
mRNA Refseq : | NM_001258040 |
Protein Refseq : | NP_001244969 |
MIM : | 142810 |
UniProt ID : | P12081 |
Chromosome Location : | 5q31.3 |
Pathway : | Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Cytosolic tRNA aminoacylation, organism-specific biosystem; Gene Expression, organism-specific biosystem; tRNA Aminoacylation, organism-specific biosystem; |
Function : | ATP binding; histidine-tRNA ligase activity; ligase activity; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
HARS-4580H | Recombinant Human HARS Protein, GST-tagged | +Inquiry |
HARS-4058M | Recombinant Mouse HARS Protein, His (Fc)-Avi-tagged | +Inquiry |
HARS-29181TH | Recombinant Human HARS, His-tagged | +Inquiry |
HARS-8500Z | Recombinant Zebrafish HARS | +Inquiry |
HARS-7483M | Recombinant Mouse HARS Protein | +Inquiry |
◆ Lysates | ||
HARS-770HCL | Recombinant Human HARS cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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