| Description : |
The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification. Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
108.7 kDa |
| AA Sequence : |
MSSASVTAFEKEHLWMYLQALGFEP GPATIACGKIVSHTHLGVNMFDKLN RDAFHIISYFLFQVLDQSLTKEVFK FCWPPFDQKSDTEFRKHCCEWIKRI SGECGSSFPQVVGSLFLSPGGPKFI HLMYHFARFVAMKYIKSNSKNSSHH FVETFNIKPQDLHKCIARCHFARSR FLQILQRQDCVTQKYQENAQLSVKQ VRNLRSECIGLENQIKKMEPYDDHS NMEEKIQKVRSLWASVNETLMFLEK EREVVSSVLSLVNQYALDGTNVAIN IPRLLLDKIEKQMFQLHIGNVYEAG KLNLLTVIQLLNEVLKVMKYERCQA DQARLTVDLHYLEKETKFQKERLSD LKHMRYRIKDDLTTIRHSVVEKQGE WHKKWKEFLGLSPFSLIKGWTPSVD LLPPMSPLSFDPASEEVYAKSILCQ YPASLPDAHKQHNQENGCRGDSDTL GALHDLANSPASFLSQSVSSSDRNS VTVLEKDTKMGTPKEKNEAISKKIP EFEVENSPLSDVAKNTESSAFGGSL PAKKSDPFQKEQDHLVEEVARAVLS DSPQLSEGKEIKLEELIDSLGSNPF LTRNQIPRTPENLITEIRSSWRKAI EMEENRTKEPIQMDVEHREVLPESL PVLHNQREFSMADFLLETTVSDFGQ SHLTEEKVISDCECVPQKHVLTSHI DEPPTQNQSDLLNKKVICKQDLECL AFTKLSETSRMETFSPAVGNRIDVM GGSEEEFMKILDHLEVSCNKPSTNK TMLWNSFQISIGISSKSFKDNDFGI LHETLPEEVGHLSFNSSSSSEANFK LEPNSPMHGGTLLEDVVGGRQTTPE SDFNLQALRSRYEALKKSLSKKREE SYLSNSQTPERHKPELSPTPQNVQT DDTLNFLDTCDLHTEHIKPSLRTSI GERKRSLSPLIKFSPVEQRLRTTIA CSLGELPNLKEEDILNKSLDAKEPP SDLTRTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
